Authored by KD Tripathi, this fourth edition is meticulously designed to align with the Dental Council of India’s curriculum. The book is divided into three sections: general pharmacological principles, systemic pharmacology, and antimicrobials relevant to dental therapeutics. It emphasizes the application of analgesics, NSAIDs, local anesthetics, and the role of various antimicrobials in orodental infections. Additionally, it provides insights into the management of common medical emergencies in dental settings, making it an indispensable resource for both students and practitioners.